E-tailers that focus on a niche will fare better. Profitable pet supplier Waggin' Tails specializes in high-margin products, unlike the defunct Pets.com, which tried to do it all.INFORMATION BROKERS
The No. 1 thing Netizens do online is look for information. Those that make it pay will win. Job-listing site Monster.com, which charges employers to post positions, makes money.THE FENCE-STRADDLERS
Businesses in both the physical and virtual worlds reign. Merck-Medco, the nation's leading provider of prescription-drug care, racking up $460 million in online sales last year, has clobbered Net upstarts drugstore.com and PlanetRx.A LA CARTE MODELS
Business models that boast multiple ways of making money have good odds. Real estate listing service Homestore.com, which sells technology and ads, will be profitable this year on projected revenues of $440 million.