The Top 25 Managers -- The Top Entrepreneurs

Mark J. Levin, Millennium Pharmaceuticals

Mark J. Levin and his wife are fixing up a 33-room mansion in Rhode Island. There's also a llama, two peacocks, and nine African sika deer to care for. But those projects are nothing compared to Levin's transformation of tiny biotech startup Millennium Pharmaceuticals Inc. (MLNM) Levin, 50, plans to use the knowledge contained in the human genome to revolutionize the pharmaceutical industry. Millennium, which has five drugs in clinical trials, will market its first, for leukemia, in early 2001. He has raised about $1.8 billion from big drug companies and others. Some of that will no doubt be used to buy up competitors and extend the house that Levin built.