Four female entrepreneurs broke the mold of unisex gear by running women-friendly companies. But they've awakened the sleeping giants -- large manufacturers who want a piece of the action. How do they plan to keep Goliath at bay?

ELLEN WESSEL Her $12.5 million Moving Comfort, a running-apparel manufacturer, plans to broaden her line to appeal to "multisport" users.

MISSY PARK Title Nine Sports mail-order catalog will add a toll-free line this fall. The $10 million company also just opened its first retail outlet, in Berkeley, Calif.

GEORGENA TERRY Her $10 million Terry Precision Bicycles started a quarterly mail-order catalog this year and just added the Women's Liberator cycling seat to its line.

SALLY McCOY Sierra Designs, a $16 million company, will publish a 70-page book this fall to help specialty retailers sell more effectively to women.