Bloomberg News

Ligand Rises on FDA Blood Drug Approval for Hepatitis C

November 19, 2012

Ligand Pharmaceuticals Inc. (LGND:US) rose the most in 14 months after its drug to help people with low blood platelet counts was approved by U.S. regulators for use in hepatitis C patients.

Ligand rose (LGND:US) 14 percent to $19.07 at the close in New York, its biggest one-day gain since August 2011. The La Jolla, California-based company said today the Food and Drug Administration approved the medicine to enable hepatitis C patients with low blood platelet counts to take interferon therapy.

The company had sold the rights to the drug to London-based GlaxoSmithKline Plc (GSK), which will pay Ligand royalties. Of the 4.2 million people in the U.S. with hepatitis C, about 3.5 percent have low blood platelet counts that disqualify them from treatment with interferon.

“Otherwise very sick patients, who had little to no therapeutic options, will now have an opportunity to potentially receive treatment for hepatitis C,” John Higgins, Ligand’s chief executive officer, said in a statement.

Interferon is given as a weekly injection for a year, carries flu-like side effects, and cures roughly half of patients.

The Ligand treatment wasn’t tested with new, experimental therapies that don’t include interferon. Pharmaceutical companies led by Gilead Sciences Inc., Abbott Laboratories and Bristol-Myers Squibb Co. are developing pill-based hepatitis C treatments in a bid to replace interferon therapies.

To contact the reporter on this story: Drew Armstrong in New York at;

To contact the editor responsible for this story: Reg Gale at

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