The following is an analysis of Orbimed Advisors LLC as of Sept. 30, according to a filing with the U.S. Securities and Exchange Commission on Nov 14.

Top Positions by Market Value 
Company Name                 Ticker      Market Value      Current     Change
                                            (USD $)       Position  In Position
Pfizer Inc                   PFE US       221,214,700    8,902,000   -1,283,600
Merck & Co. Inc.             MRK US       209,195,705    4,639,000    1,157,500
Gilead Sciences Inc          GILD US      198,114,444    2,986,800       57,800
Abbott Laboratories          ABT US       172,359,840    2,514,000      526,000
Onyx Pharmaceuticals Inc     ONXX US      128,718,850    1,523,300     -135,000
Biogen Idec Inc              BIIB US      117,890,821      790,100       12,700
Express Scripts Holding Co   ESRX US      109,318,786    1,745,470      -52,100
Life Technologies Corp       LIFE US       94,304,806    1,930,300     -113,700
Bristol-Myers Squibb Co      BMY US        90,858,375    2,692,100   -2,387,000
Watson Pharmaceuticals Inc   WPI US        84,308,400      990,000     -147,800
 
 
Top New Buys by Market Value 
Company Name                 Ticker      Market Value      Current     Change
                                            (USD $)       Position  In Position
Infinity Pharmaceuticals Inc INFI US       44,462,112    1,891,200    1,891,200
MAKO Surgical Corp           MAKO US       20,016,277    1,149,700    1,149,700
XenoPort Inc                 XNPT US       13,582,031    1,186,100    1,186,100
Repros Therapeutics Inc      RPRX US        9,000,930      591,000      591,000
Achillion Pharmaceuticals    ACHN US        5,400,195      519,000      519,000
 
 
Top Sell Outs by Market Value 
Company Name                 Ticker         MV Change      Current     Change
                                            (USD $)       Position  In Position
Questcor Pharmaceuticals     QCOR US      -70,399,252            0   -1,322,300
Elan Corp Plc -Spons ADR     ELN US       -48,438,800            0   -3,320,000
ChemoCentryx Inc             CCXI US      -36,070,725            0   -2,404,715
Johnson & Johnson            JNJ US       -30,462,804            0     -450,900
Shire Plc-ADR                SHPG US      -27,325,157            0     -316,300
 
 
Top Position Increases by Market Value 
Company Name                 Ticker         MV Change      Current     Change
                                            (USD $)       Position  In Position
Merck & Co. Inc.             MRK US        63,843,080    4,639,000    1,157,500
Gilead Sciences Inc          GILD US       47,915,324    2,986,800       57,800
Abbott Laboratories          ABT US        44,193,480    2,514,000      526,000
Medivation Inc               MDVN US       40,676,350      777,000      709,000
Affymax Inc                  AFFY US       30,297,312    2,638,000      676,900
 
 
Top Position Decreases By Market Value 
Company Name                 Ticker         MV Change      Current     Change
                                            (USD $)       Position  In Position
Bristol-Myers Squibb Co      BMY US       -91,735,270    2,692,100   -2,387,000
Auxilium Pharmaceuticals Inc AUXL US      -68,986,889       60,000   -2,560,100
Baxter International Inc     BAX US       -27,255,570      524,000     -583,000
Warner Chilcott PLC-Class A  WCRX US      -21,762,061    3,219,400     -418,300
Allergan Inc                 AGN US       -20,217,167      411,300     -214,000
 
 
SOURCE: SEC 13F-HR 
FILER: Orbimed Advisors LLC 
QUARTER ENDED: 09/30/2012 
SEC RECEIVED: 11/14/2012 

To contact the reporter on this story: Julie Sinatra in Princeton at jshuwall@bloomberg.net.

To contact the editor responsible for this story: Rodney Yap at ryap@bloomberg.net.