The BusinessWeek 50

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As our 13th annual ranking of the BW 50 shows, innovation is still alive and well—vital, even—among America's largest companies

Sift through our interactive ranking to see how the best performing companies stack up on any number of financial measures

Our list is chock-full of companies that changed the rules of engagement in their industries

BusinessWeek chief economist Michael Mandel and senior writer Dean Foust discuss the BW 50

The methodology for selecting the BW 50 focuses on two financial measures—return on capital and growth

Gilead owes much of its success to making it easier for patients to comply with complex and uncomfortable drug regimens

Its global market share is at a record high as it prepares to crank up its innovation machine

With their wages tied to productivity, the steelmaker's workers are hurting. But they're still on the job, as Nucor waits for a turnaround

By making the right bets at the right time, and using technology to make them pay, Occidental has outperformed giants like ExxonMobil

To find the most promising stocks, we put our list through screens designed to find companies that Wall Street's savviest would buy

Jeffrey Sprecher's ICE is the frontrunner in the battle to dominate the new frontier for exchanges: trading derivatives