NEW YORK (AP) — A look at the 10 biggest percentage gainers on Nasdaq at the close of trading:

WashingtonFirst Bankshares rose 27.3 percent to $14.00.

Perion Network Ltd. rose 20.1 percent to $11.35.

Isis Pharmaceuticals Inc. rose 12.0 percent to $11.92.

Parametric Sound Corp. rose 11.9 percent to $9.22.

China Natural Resources Inc. rose 11.8 percent to $5.50.

Medicines Co. (MDCO) rose 11.7 percent to $28.83.

Consumer Portfolio Services Inc. rose 11.4 percent to $6.25.

Compugen Ltd. rose 11.4 percent to $5.69.

Tangoe Inc. rose 10.9 percent to $14.69.

Arena Pharmaceuticals Inc. rose 9.9 percent to $10.11.