BUSINESSWEEK ONLINE : DECEMBER 11, 2000 ISSUE
SCIENCE & TECHNOLOGY

It's Back-Mending Work


The spinal cord consists of long nerve cells called axons, surrounded by protective vertebrae. Axons carry signals back and forth from the brain, controlling the body's movements. If these axons are crushed or severed, paralysis results. Scientists are working on three potential treatments:

REGROWING
Researchers have discovered the chemical signals that block the regrowth of damaged axons. Antibodies to these ''stop'' signals have been developed.

REPLACING
Scientists are hopeful that stem cells, the precursor cells that give rise to all others, will turn into new nerve cells when injected into damaged spines.

RETRAINING
Axons have some ability to make decisions without instructions from the brain. So, scientists hope that repeated exercises can retrain undamaged nerve cells to take over the functions of the damaged ones.



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Rebuilding the Spinal Cord

TABLE: It's Back-Mending Work



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