BUSINESSWEEK ONLINE : NOVEMBER 13, 2000 ISSUE
SCIENCE & TECHNOLOGY Breaching Cancer's Defense How Aptosyn blocks cancer cells' efforts to avoid a process called programmed cell death 1. Cells continuously die off and are replaced by new cells. The process starts when certain ''death genes'' trigger the release of death enzymes that prompt cells to die off. 2. But cancerous cells emit counteracting ''protector'' enzymes whose purpose is to block the death enzymes from reaching the cell's surface, where they would activate its cell-death program. 3. Aptosyn mops up cancer-cell-produced protector enzymes before they can block the cell-death enzymes, allowing them to continue unimpeded. The end result: The cancer cells die off, and the tumor disappears. _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _					RELATED ITEMS Cell Pathways: Blockbuster or Bust TABLE: Breaching Cancer's Defense INTERACT E-Mail to Business Week Online

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