BUSINESSWEEK ONLINE : APRIL 10, 2000 ISSUE
SCIENCE & TECHNOLOGY Proteomics 101 Proteomics promises to help scientists identify novel drug targets faster. Here's one way to do it: STEP 1 Researchers compare patterns of proteins in spinal fluid from a normal patient and an Alzheimer's patient. That reveals proteins present only in Alzheimer's patients. STEP 2 Such proteins are isolated and treated to produce a unique fingerprint. That fingerprint is compared with others on file, identifying the protein. STEP 3 This allows researchers to develop a drug to block its activity. _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _ _					RELATED ITEMS Beyond the Genome: Biotech's Next Holy Grail TABLE: Proteomics 101 TABLE: Out in Front First Silicon. Then DNA. And Soon, Protein Chips Tobacco Turns Over a New Leaf INTERACT E-Mail to Business Week Online

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