DRUG/MANUFACTURER            ACTION                           

CELEBREX                     Suppresses enzymes               
(Searle, Pfizer)             that promote joint inflammation  

ENBREL                       Mimics receptor for              
(Immunex, Wyeth-Ayerst)      protein in inflamed joints       

ARAVA                        Targets fast-growing white blood 
(Hoechst Marion Roussel)     cells that trigger inflammation  

CORTICOSTEROIDS              Hormones that suppress inflam-   
(Various)                    mation--and the immune system

NONSTEROIDAL ANTI-           Inhibit enzymes                  
INFLAMMATORIES (Various)     involved in joint inflammation   

METHATREXATE                 Cancer drug that suppresses      
(Various)                    all fast-growing cells           


DRUG/MANUFACTURER           SIDE EFFECTS

CELEBREX                    Diarrhea,
(Searle, Pfizer)            abdominal pain

ENBREL                      Injection-site
(Immunex, Wyeth-Ayerst)     reactions

ARAVA                       Diarrhea, rash,
(Hoechst Marion Roussel)    hair loss

CORTICOSTEROIDS             Weight gain,
(Various)                   diabetes,
                            hypertension 

NONSTEROIDAL ANTI-          Stomach ulcers,
INFLAMMATORIES (Various)    intestinal bleeding

METHATREXATE                Infections,
(Various)                   liver failure