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The Search for Function

Much of the promising work on commercial applications of genetics is occurring at small companies. Some are already publicly traded; others might help their larger partners strike it rich.

AFFYMETRIX*: SANTA CLARA, CALIF. DNA chips. Deals with Hoffmann-La Roche, Merck, and Glaxo.

CADUS*: TARRYTOWN, N.Y. Studying yeast. Deals with SmithKline Beecham, Bristol-Myers Squibb, and Solvay.

EXELIXIS: CAMBRIDGE, MASS. Fruit flies. Private co. raised $16 million, IPO expected next year. No announced deals yet.

GENSET*: PARIS Strength is in finding regulatory regions for genes. Deals with Synthelabo, Johnson & Johnson.

HUMAN GENOME SCIENCES*: ROCKVILLE, MD. Strong sequencing company. Deals with SKB and Merck DGaA.

INCYTE*: PALO ALTO, CALIF. Combines huge DNA database with chips. Deals with Pfizer, Upjohn, and 8 others.

MILLENNIUM*: CAMBRIDGE, MASS. Gene hunters plus strong functional capabilities. Deals with Hoffmann-LaRoche, Lilly.

NEMAPHARM: CAMBRIDGE, MASS. Studying nematodes, now owned by Sequana. Deal with Glaxo.

*PUBLICLY TRADED
DATA: BW


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